CE Information and Faculty Disclosures

• TARGET AUDIENCE
  This activity has been designed to meet the educational needs of oncology nurses, nurse practitioners and clinical nurse specialists involved in the treatment of lymphomas.
  
  PURPOSE STATEMENT
  By providing information on the latest research developments in the context of expert perspectives, this CNE activity will assist oncology nurses, nurse practitioners and clinical nurse specialists with the formulation of state-of-the-art clinical management strategies to facilitate optimal care of patients with lymphomas.
  
  LEARNING OBJECTIVES

  • Review recent therapeutic advances and related FDA authorizations for newly diagnosed and relapsed/refractory (R/R) follicular lymphoma (FL), mantle cell lymphoma (MCL), diffuse large B-cell lymphoma (DLBCL), HL and peripheral T-cell lymphoma (PTCL), and use this information to enhance decision-making for patients.
  • Appraise the rationale for and available data documenting the utility of lenalidomide in combination with rituximab for newly diagnosed and R/R FL, and use this information to counsel patients regarding what role, if any, this regimen should play in their care.
  • Recognize the relevance of prior therapeutic exposure and patient and disease characteristics to the selection and sequencing of available systemic treatments for patients with R/R FL or MCL.
  • Appraise the similarities and differences among commercially available Bruton tyrosine kinase inhibitors, and counsel patients regarding the selection and sequencing of these agents in the management of R/R MCL.
  • Develop an understanding of the biologic rationale for and appreciate available efficacy and safety data with chimeric antigen receptor T-cell therapy, and identify patients with R/R DLBCL and other lymphomas for whom this approach may be appropriate.
  • Consider available clinical trial data and the scientific rationale for the evaluation of brentuximab vedotin in combination with AVD (doxorubicin/vinblastine/dacarbazine) to discern how this regimen can be optimally incorporated into front-line management of advanced classical HL.
  • Educate patients about the side effects associated with approved therapies commonly used in the management of FL, MCL, DLBCL, HL and PTCL, and provide preventive strategies to reduce or ameliorate these toxicities.
  • Describe available and emerging data with other investigational agents and strategies currently under evaluation for FL, MCL, DLBCL, HL and PTCL, and where applicable, refer eligible patients for trial participation.
  • Identify opportunities to enhance the collaborative role of oncology nurses in the comprehensive biopsychosocial care of patients with Hodgkin and non-Hodgkin lymphomas to optimize clinical and quality-of-life outcomes.

  ACCREDITATION STATEMENT
  Research To Practice (RTP) is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center’s (ANCC) Commission on Accreditation.
  
  CREDIT DESIGNATION STATEMENTS
  CME credit is no longer available for this issue
  
  ONCC/ILNA CERTIFICATION INFORMATION
  CME credit is no longer available for this issue
  
  FOR SUCCESSFUL COMPLETION
  CME credit is no longer available for this issue
  
  CONTENT VALIDATION AND DISCLOSURES
  RTP is committed to providing its participants with high-quality, unbiased and state-of-the-art education. We assess conflicts of interest with faculty, planners and managers of CNE (NCPD) activities. Conflicts of interest are identified and resolved through a conflict of interest resolution process. In addition, all activity content is reviewed by both a member of the RTP scientific staff and an external, independent reviewer for fair balance, scientific objectivity of studies referenced and patient care recommendations.
  
  FACULTY — The following faculty (and their spouses/partners) reported relevant conflicts of interest, which have been resolved through a conflict of interest resolution process:
  
  Kim Leake, MSN, FNP-C
  UVA Health
  Division of Hematology/Oncology
  Emily Couric Cancer Center
  Charlottesville, Virginia
  
  No financial interests or affiliations to disclose.
  
  Mollie Moran, APRN-CNP, AOCNP
  The James Cancer Hospital at The Ohio State University
  Columbus, Ohio
  
  No financial interests or affiliations to disclose.
  
  Craig Moskowitz, MD
  Physician in Chief, Oncology Service Line
  Sylvester Comprehensive Cancer Center
  Professor of Medicine, Miller School of Medicine
  University of Miami Health System
  Miami, Florida
  
  Advisory Committee: AstraZeneca Pharmaceuticals LP, Bristol-Myers Squibb Company, Merck, Seattle Genetics, Takeda Oncology; Contracted Research: ADC Therapeutics SA, AstraZeneca Pharmaceuticals LP, Merck, Seattle Genetics.
  
  Michael E Williams, MD, ScM
  Byrd S Leavell Professor of Medicine
  Chief, Hematology/Oncology Division
  Physician Lead, Cancer Service Line
  University of Virginia School of Medicine
  Charlottesville, Virginia
  
  Advisory Committee: AbbVie Inc; Consulting Agreements: Celgene Corporation, Gilead Sciences Inc, TG Therapeutics Inc; Contracted Research: Allos Therapeutics, Celgene Corporation, Gilead Sciences Inc, Janssen Biotech Inc, Pharmacyclics LLC, an AbbVie Company, TG Therapeutics Inc; Speakers Bureau: Xian Janssen Pharmaceutical Ltd.
  
  MODERATOR — Dr Love is president and CEO of Research To Practice. Research To Practice receives funds in the form of educational grants to develop CME/CNE activities from the following commercial interests: AbbVie Inc, Acerta Pharma — A member of the AstraZeneca Group, Adaptive Biotechnologies, Agendia Inc, Agios Pharmaceuticals Inc, Amgen Inc, Array BioPharma Inc, a subsidiary of Pfizer Inc, Astellas, AstraZeneca Pharmaceuticals LP, Bayer HealthCare Pharmaceuticals, Biodesix Inc, bioTheranostics Inc, Blueprint Medicines, Boehringer Ingelheim Pharmaceuticals Inc, Boston Biomedical Inc, Bristol-Myers Squibb Company, Celgene Corporation, Clovis Oncology, Daiichi Sankyo Inc, Dendreon Pharmaceuticals Inc, Eisai Inc, EMD Serono Inc, Exelixis Inc, Foundation Medicine, Genentech, a member of the Roche Group, Genmab, Genomic Health Inc, Gilead Sciences Inc, GlaxoSmithKline, Grail Inc, Guardant Health, Halozyme Inc, Helsinn Healthcare SA, ImmunoGen Inc, Incyte Corporation, Infinity Pharmaceuticals Inc, Ipsen Biopharmaceuticals Inc, Janssen Biotech Inc, administered by Janssen Scientific Affairs LLC, Jazz Pharmaceuticals Inc, Kite, A Gilead Company, Lexicon Pharmaceuticals Inc, Lilly, Loxo Oncology Inc, a wholly owned subsidiary of Eli Lilly & Company, Merck, Merrimack Pharmaceuticals Inc, Myriad Genetic Laboratories Inc, Natera Inc, Novartis, Oncopeptides, Pfizer Inc, Pharmacyclics LLC, an AbbVie Company, Prometheus Laboratories Inc, Puma Biotechnology Inc, Regeneron Pharmaceuticals Inc, Sandoz Inc, a Novartis Division, Sanofi Genzyme, Seattle Genetics, Sirtex Medical Ltd, Spectrum Pharmaceuticals Inc, Taiho Oncology Inc, Takeda Oncology, Tesaro, A GSK Company, Teva Oncology, Tokai Pharmaceuticals Inc, Tolero Pharmaceuticals and Verastem Inc.
  
  RTP CNE (NCPD) PLANNING COMMITTEE MEMBERS, STAFF AND REVIEWERS — Planners, scientific staff and independent reviewers for RTP have no relevant conflicts of interest to disclose.
  
  This educational activity contains discussion of published and/or investigational uses of agents that are not indicated by the Food and Drug Administration. Research To Practice does not recommend the use of any agent outside of the labeled indications. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications and warnings. The opinions expressed are those of the presenters and are not to be construed as those of the publisher or grantors.
  
  This activity is supported by educational grants from AstraZeneca Pharmaceuticals LP, Celgene Corporation, Pharmacyclics LLC, an AbbVie Company, and Janssen Biotech Inc, administered by Janssen Scientific Affairs LLC, and Seattle Genetics.
  
  Hardware/Software Requirements:
  A high-speed Internet connection
  A monitor set to 1280 x 1024 pixels or more
  Internet Explorer 11 or later, Firefox 56 or later, Chrome 61 or later, Safari 11 or later, Opera 48 or later
  Adobe Flash Player 27 plug-in or later
  Adobe Acrobat Reader
  (Optional) Sound card and speakers for audio
  
  Release date: August 2020
  Expiration date: August 2021
  
  There is no implied or real endorsement of any product by RTP or the American Nurses Credentialing Center.