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Meet The Professor: Current and Future Role of Immunotherapy in the Management of Lung Cancer — Part 2 of a 4-Part Series (Webinar Audio Proceedings)
Released March 2022

Featuring perspectives from Dr Jarushka Naidoo. Published March 8, 2022. (Webinar Audio Proceedings)

CE Information and Faculty Disclosures

    This program is intended for medical oncologists, hematologists, hematology-oncology fellows and other allied healthcare professionals involved in the treatment of lung cancer.


    • Analyze the biologic basis for the investigation of immune checkpoint inhibitors for patients with non-metastatic non-small cell lung cancer (NSCLC) and evaluate available data documenting the efficacy and safety of anti-PD-1/PD-L1 antibodies as neoadjuvant or adjuvant therapy.
    • Appreciate emerging Phase III findings with the use of an anti-PD-L1 antibody following the completion of chemotherapy and surgery for patients with resectable NSCLC, and consider the potential effect of this information on current and future clinical practice.
    • Appraise the FDA approval of anti-PD-L1 antibody consolidation for patients with unresectable Stage III NSCLC who have not experienced disease progression after standard platinum-based chemotherapy concurrent with radiation therapy, and discern how this strategy can be integrated safely into routine clinical practice.
    • Review recent therapeutic advances related to the use of anti-PD-1/PD-L1 antibodies as monotherapy or in combination with chemotherapy, chemobiologic therapy or other immunotherapy for metastatic NSCLC and consider the clinical and biologic factors affecting the recommendation of one approach versus the others.
    • Recognize the recent FDA approvals of nivolumab in combination with ipilimumab with and without chemotherapy as first-line treatment for patients with metastatic NSCLC and appropriately incorporate these novel regimens into current treatment algorithms.
    • Acknowledge emerging Phase III research data documenting the efficacy of durvalumab in combination with tremelimumab and chemotherapy as first-line treatment for NSCLC, and examine the potential future role of this novel regimen.
    • Evaluate the FDA approvals of atezolizumab and durvalumab in combination with platinum-based chemotherapy as first-line therapy for patients with extensive-stage small cell lung cancer (SCLC), and consider how these approaches can be integrated appropriately and safely into clinical practice.
    • Review the scientific justification for the investigation of immune checkpoint inhibitors in patients with malignant pleural mesothelioma (MPM) and evaluate the current clinical role of nivolumab in combination with ipilimumab as first-line therapy for unresectable disease.
    • Recall the designs of ongoing clinical trials and emerging efficacy data of studies evaluating novel anti-PD-1/PD-L1 antibody-based approaches for patients with NSCLC, SCLC and MPM and counsel appropriate patients about availability and participation.

    Research To Practice is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

    CME credit is no longer available for this issue

    CME credit is no longer available for this issue

    Audio Program: This CME activity consists of an audio component.
    CME credit is no longer available for this issue

    Video Program: This CME activity consists of a video component.
    CME credit is no longer available for this issue

    Research To Practice (RTP) is committed to providing its participants with high-quality, unbiased and state-of-the-art education and adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of an accredited continuing education activity, including faculty, planners, reviewers or others are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of this activity. In addition, all activity content is reviewed by RTP scientific staff and an external, independent physician reviewer for fair balance, scientific objectivity of studies referenced and patient care recommendations.

    FACULTY — The following faculty reported relevant financial relationships with ineligible entities:

    Jarushka Naidoo, MB BCH, MHS
    Beaumont Hospital Dublin, Ireland
    Johns Hopkins University
    Baltimore, Maryland

    Advisory Committee and Consulting Agreements: AstraZeneca Pharmaceuticals LP, Daiichi Sankyo Inc, Genentech, a member of the Roche Group, Merck, Pfizer Inc, Takeda Pharmaceuticals USA Inc; Contracted Research: AstraZeneca Pharmaceuticals LP, Merck; Data and Safety Monitoring Board/Committee: Daiichi Sankyo Inc.

    MODERATOR — Dr Love is president and CEO of Research To Practice. Research To Practice receives funds in the form of educational grants to develop CME activities from the following companies: AbbVie Inc, Adaptive Biotechnologies Corporation, ADC Therapeutics, Agios Pharmaceuticals Inc, Alexion Pharmaceuticals, Amgen Inc, Array BioPharma Inc, a subsidiary of Pfizer Inc, Astellas, AstraZeneca Pharmaceuticals LP, Aveo Pharmaceuticals, Bayer HealthCare Pharmaceuticals, BeiGene Ltd, BeyondSpring Pharmaceuticals Inc, Blueprint Medicines, Boehringer Ingelheim Pharmaceuticals Inc, Bristol-Myers Squibb Company, Celgene Corporation, Clovis Oncology, Coherus BioSciences, Daiichi Sankyo Inc, Eisai Inc, EMD Serono Inc, Epizyme Inc, Exact Sciences, Exelixis Inc, Five Prime Therapeutics Inc, Foundation Medicine, G1 Therapeutics Inc, Genentech, a member of the Roche Group, Genmab, Gilead Sciences Inc, GlaxoSmithKline, Grail Inc, Halozyme Inc, Helsinn Healthcare SA, ImmunoGen Inc, Incyte Corporation, Ipsen Biopharmaceuticals Inc, Janssen Biotech Inc, administered by Janssen Scientific Affairs LLC, Jazz Pharmaceuticals Inc, Karyopharm Therapeutics, Kite, A Gilead Company, Lilly, Loxo Oncology Inc, a wholly owned subsidiary of Eli Lilly & Company, Merck, Mersana Therapeutics Inc, Natera Inc, Novartis, Novocure Inc, Oncopeptides, Pfizer Inc, Pharmacyclics LLC, an AbbVie Company, Puma Biotechnology Inc, Regeneron Pharmaceuticals Inc, Sanofi Genzyme, Seagen Inc, Servier Pharmaceuticals LLC, Sumitomo Dainippon Pharma Oncology Inc, Taiho Oncology Inc, Takeda Pharmaceuticals USA Inc, Tesaro, A GSK Company, TG Therapeutics Inc, Turning Point Therapeutics Inc, Verastem Inc and Zymeworks Inc.

    RESEARCH TO PRACTICE CME PLANNING COMMITTEE MEMBERS, STAFF AND REVIEWERS — Planners, scientific staff and independent reviewers for Research To Practice have no relevant conflicts of interest to disclose.

    This educational activity contains discussion of published and/or investigational uses of agents that are not indicated by the Food and Drug Administration. Research To Practice does not recommend the use of any agent outside of the labeled indications. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications and warnings. The opinions expressed are those of the presenters and are not to be construed as those of the publisher or grantors.

    These activities are supported by educational grants from Eisai Inc, Genentech, a member of the Roche Group, and Regeneron Pharmaceuticals Inc and Sanofi Genzyme.

    Release date: March 2022
    Expiration date: March 2023

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(WIFI is recommended for best performance):

Adjuvant and Neoadjuvant Immunotherapy

Consolidation and Immunotherapy After Chemoradiation for Unresectable Locally Advanced Non-Small Cell Lung Cancer

Immunotherapy for Metastatic Disease

Immunotherapy in Mesothelioma

Immunotherapy and Novel Agents in Small Cell Lung Cancer

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