Would you offer an Oncotype DX assay for an otherwise healthy 60-year-old patient with a Grade II, MSS T4N0 (0 out of 20 nodes positive) tumor?
If not, what adjuvant systemic therapy would you likely recommend for this patient?
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Shi Q et al. Comparison of outcomes after fluorouracil-based adjuvant therapy for stages II and III colon cancer between 1978 to 1995 and 1996 to 2007: Evidence of stage migration from the ACCENT database. J Clin Oncol 2013;31(29):3656-63. Abstract
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