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Which EGFR Ab preferred 1st as Tx for mCRC? Ever use other EGFR Ab later?

Which EGFR antibody do you usually use first in the treatment of mCRC?

Do you usually use the other EGFR antibody at a later point in treatment?

Douillard JY et al. Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: The PRIME study. J Clin Oncol 2010;28(31):4697-705. Abstract

Haraldsdottir S et al. Integrating anti-EGFR therapies in metastatic colorectal cancer. J Gastrointest Oncol 2013;4(3):285-98. Abstract

Lang I et al. Quality of life analysis in patients with KRAS wild-type metastatic colorectal cancer treated first-line with cetuximab plus irinotecan, fluorouracil and leucovorin. Eur J Cancer 2013;49(2):439-48. Abstract

Peeters M et al. Randomized phase III study of panitumumab with fluorouracil, leucovorin, and irinotecan (FOLFIRI) compared with FOLFIRI alone as second-line treatment in patients with metastatic colorectal cancer. J Clin Oncol 2010;28(31):4706-13. Abstract

Van Cutsem E et al. Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: Updated analysis of overall survival according to tumor KRAS and BRAF mutation status. J Clin Oncol 2011;29(15):2011-9. Abstract

Van Cutsem E et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med 2009;360(14):1408-17. Abstract