Survey of 100 Practicing Medical Oncologists on Clinical Scenarios and Patient Cases Presented by Contributing Faculty Members Drs Eric P Winer and Joseph A Sparano. (Text and Audio Content)
OVERVIEW OF ACTIVITY
It is important for medical oncologists, hematologists and fellows to be aware of similarities and differences between their patterns of cancer care and those of other community practitioners. Additionally, the recognition that heterogeneity exists within the treating oncology community underscores the existence of clinical situations for which the research evidence to support a single definitive approach may be suboptimal.
This program focuses on the self-described practice patterns of randomly selected community medical oncologists and hematologists in a variety of key clinical scenarios in breast cancer. Also included are clinical investigator commentaries describing clinical scenario-related treatment selections and management patterns. This CME program provides medical oncologists, hematologists and hematology-oncology fellows with information on national cancer patterns of care to assist with the development of best-practice clinical management strategies for breast cancer.
LEARNING OBJECTIVES
ACCREDITATION STATEMENT
Research To Practice is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
CME credit is no longer available for this issue
CREDIT DESIGNATION STATEMENT
CME credit is no longer available for this issue
HOW TO USE THIS CME ACTIVITY
CME credit is no longer available for this issue
This CME activity contains both audio and print components. The participant should listen to the audio MP3s and read the text portion. The text portion of this activity contains edited comments, clinical trial schemas, graphics and references that supplement the audio MP3s, as well as links to relevant full-text articles, abstracts, trial information and other web resources.
COMMERCIAL SUPPORT
This program is supported by educational grants from Genentech BioOncology, Genomic Health Inc and Sanofi-Aventis.
PHARMACEUTICAL AGENTS DISCUSSED IN THIS PROGRAM
This educational activity includes discussion of published and/or investigational uses of agents that are not indicated by the Food and Drug Administration. Research To Practice does not recommend the use of any agent outside of the labeled indications. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications and warnings. The opinions expressed are those of the presenters and are not to be construed as those of the publisher or grantors.
CONTENT VALIDATION AND DISCLOSURES
Research To Practice (RTP) is committed to providing its participants with high-quality, unbiased and state-of-the-art education. We assess potential conflicts of interest with faculty, planners and managers of CME activities. Real or apparent conflicts of interest are identified and resolved through a conflict of interest resolution process. In addition, all activity content is reviewed by both a member of the RTP scientific staff and an external, independent physician reviewer for fair balance, scientific objectivity of studies
referenced and patient care recommendations.
CME DISCLOSURES FOR QUOTED FACULTY
Drs Burstein, Carey, Geyer, Goss, Gralow and Osborne, Prof Untch and Drs Winer and Wolff had no real or apparent conflicts of interest to disclose. The following faculty (and their spouses/partners) reported real or apparent conflicts of interest, which have been resolved through a conflict of interest resolution process: Dr Brufsky — Consulting Agreements: Genentech BioOncology, Novartis Pharmaceuticals Corporation; Speakers Bureau: Novartis Pharmaceuticals Corporation, Sanofi-Aventis. Dr Cobleigh — Advisory Committee: Eisai Inc, Genentech BioOncology, Genomic Health Inc; Paid Research: Genentech BioOncology. Dr Ellis — Advisory Committee: AstraZeneca Pharmaceuticals LP, Bristol-Myers Squibb Company, Genentech BioOncology, GlaxoSmithKline, Merck and Company Inc, Novartis Pharmaceuticals Corporation, Pfizer Inc. Dr Gianni — Advisory Committee: Biogen Idec, Boehringer Ingelheim Pharmaceuticals Inc, Celgene Corporation, Eisai Inc, Genentech BioOncology, Genomic Health Inc, GlaxoSmithKline, Millennium — The Takeda Oncology Company, Novartis Pharmaceuticals Corporation, Onyx Pharmaceuticals Inc, Roche Laboratories Inc, Sanofi-Aventis; Consulting Agreements: Biogen Idec, GlaxoSmithKline, Millennium — The Takeda Oncology Company. Dr Gradishar — Advisory Committee: Abraxis BioScience Inc, a wholly owned subsidiary of Celgene Corporation, Amgen Inc, AstraZeneca Pharmaceuticals LP, Bayer HealthCare Pharmaceuticals, Bristol-Myers Squibb Company, Eisai Inc, EMD Serono Inc, Genentech BioOncology, GlaxoSmithKline, Novartis Pharmaceuticals Corporation, Onyx Pharmaceuticals Inc, Roche Laboratories Inc, Sanofi-Aventis. Dr Krop — Paid Research: Genentech BioOncology, Novartis Pharmaceuticals Corporation. Dr Mackey — Advisory Committee: Amgen Inc, Genentech BioOncology, Genomic Health Inc, ImClone Systems Incorporated, Pfizer Inc, Roche Laboratories Inc, Sanofi-Aventis. Dr Miller — Advisory Committee: Genentech BioOncology, MethylGene Inc, Roche Laboratories Inc; Speakers Bureau: Genentech Bio-Oncology, Roche Laboratories Inc. Dr Muss — Consulting Agreements: Abraxis BioScience Inc, a wholly owned subsidiary of Celgene Corporation, Amgen Inc, Boehringer Ingelheim Pharmaceuticals Inc, Bristol-Myers Squibb Company, Pfizer Inc, Roche Laboratories Inc, Sandoz, Wyeth. Dr O’Shaughnessy — Advisory Committee: Genentech BioOncology; Speakers Bureau: Abraxis BioScience Inc, a wholly owned subsidiary of Celgene Corporation, AstraZeneca Pharmaceuticals LP, Bristol-Myers Squibb Company, Genentech BioOncology; Lilly USA LLC, Sanofi-Aventis. Dr Pegram — Advisory Committee: Amgen Inc, Genentech BioOncology, Genomic Health Inc, GlaxoSmithKline, Sanofi-Aventis; Consulting Agreements: Genentech BioOncology, GlaxoSmithKline, Novartis Pharmaceuticals Corporation, Sanofi-Aventis; Data and Safety Monitoring Board: Wyeth; Paid Research: Genentech BioOncology, Sanofi-Aventis; Speakers Bureau: AstraZeneca Pharmaceuticals LP, Genentech BioOncology, Genomic Health Inc, GlaxoSmithKline, Pfizer Inc, Sanofi-Aventis. Dr Perez — Paid Research: AstraZeneca Pharmaceuticals LP, Genentech BioOncology, GlaxoSmithKline, Roche Laboratories Inc, Sanofi-Aventis. Dr Piccart-Gebhart — Advisory Committee and Consulting Agreements: Bayer HealthCare Pharmaceuticals, Bristol-Myers Squibb Company, GlaxoSmithKline, Novartis Pharmaceuticals Corporation, Onyx Pharmaceuticals Inc, Pfizer Inc, Roche Laboratories Inc, Sanofi-Aventis. Dr Press — Advisory Committee: GlaxoSmithKline; Paid Research: Genentech BioOncology, GlaxoSmithKline. Dr Robert — Advisory Committee and Paid Research: Sanofi-Aventis; Consulting Agreement: Novartis Pharmaceuticals Corporation; Speakers Bureau: Roche Laboratories Inc. Prof Robertson — Advisory Committee: AstraZeneca Pharmaceuticals LP, Bayer HealthCare Pharmaceuticals; Consulting Agreement and Stock Ownership: Oncimmune Ltd; Paid Research: Amgen Inc, AstraZeneca Pharmaceuticals LP, Bayer HealthCare Pharmaceuticals, Oncimmune Ltd; Speakers Bureau: AstraZeneca Pharmaceuticals LP, GlaxoSmithKline. Dr Slamon — Honoraria: Genentech BioOncology, Pfizer Inc, Roche Laboratories Inc, Sanofi-Aventis; Paid Travel: Genentech BioOncology, Roche Laboratories Inc, Sanofi-Aventis; Stock Ownership: Amgen Inc, Pfizer Inc, Schering-Plough Corporation. Prof Smith — Advisory Committee: Bayer HealthCare Pharmaceuticals, Genentech BioOncology, Pfizer Inc, Roche Laboratories Inc, Sanofi-Aventis; Lecturing: GlaxoSmithKline, Roche Laboratories Inc. Dr Sparano — Advisory Committee: Abraxis Bio-Science Inc, a wholly owned subsidiary of Celgene Corporation, Bristol-Myers Squibb Company, Eisai Inc, Genentech BioOncology, Pfizer Inc; Consulting Agreement: Eisai Inc; Speakers Bureau: BristolMyers Squibb Company, Genentech BioOncology, GlaxoSmithKline. Dr Swain — Paid Research: Bristol-Myers Squibb Company, Genentech BioOncology; Paid Travel: Sanofi-Aventis. Dr Vahdat — Consulting Agreement: Eisai Inc; Paid Research and Speakers Bureau: Bristol-Myers Squibb Company.
EDITOR — Dr Love is president and CEO of Research To Practice, which receives funds in the form of educational grants to develop CME activities from the following commercial interests: Abraxis BioScience Inc, a wholly owned subsidiary of Celgene Corporation, Allos Therapeutics, Amgen Inc, AstraZeneca Pharmaceuticals LP, Aureon Laboratories Inc, Bayer HealthCare Pharmaceuticals/Onyx Pharmaceuticals Inc, Biogen Idec, Boehringer Ingelheim Pharmaceuticals Inc, Bristol-Myers Squibb Company, Celgene Corporation, Cephalon Inc, Daiichi Sankyo Inc, Dendreon Corporation, Eisai Inc, EMD Serono Inc, Genentech BioOncology, Genomic Health Inc, Lilly USA LLC, Millennium — The Takeda Oncology Company, Mundipharma International Limited, Myriad Genetics Inc, Novartis Pharmaceuticals Corporation, OSI Oncology, Sanofi-Aventis and Seattle Genetics.
RESEARCH TO PRACTICE STAFF AND EXTERNAL REVIEWERS — The scientific staff and reviewers for Research To Practice have no real or apparent conflicts of interest to disclose.
Hardware/Software Requirements:
An Internet connection that is at least 28.8 Kbps
A monitor set to 1280 x 1024 pixels or more
Internet Explorer 6.x or newer, Firefox 2.x or newer, or Safari 2.x or newer
Macromedia Flash plug-in 6.0 or greater
Adobe Acrobat Reader
(Optional) Sound card and speakers for audio
Last review date: April 2011
Expiration date: April 2012
Survey of 100 Practicing Medical Oncologists on Clinical Scenarios and Patient Cases Presented by Contributing Faculty Members Drs Eric P Winer and Joseph A Sparano. (Text and Audio Content)