CE Information and Faculty Disclosures

• TARGET AUDIENCE
  This program is intended for medical oncologists, hematologists, hematology-oncology fellows, radiation oncologists, surgeons and other allied healthcare professionals involved in the treatment of cancer.
  
  LEARNING OBJECTIVES

  • Effectively apply results of practice-changing clinical research to the care of patients with breast, gastrointestinal, genitourinary, gynecologic, lung and select hematologic cancers.
  • Appraise the clinical relevance of recent pivotal cancer research published in peer-reviewed journals or presented at major oncology conferences.
  • Recall ongoing trials of therapies for select hematologic cancers and solid tumors, and appropriately refer patients for study participation.
  • Use an understanding of tumor biomarkers and single and multigene signatures to individualize the care of patients with cancer.
  • Educate patients with diverse hematologic cancers and solid tumors about the benefits and risks of new therapeutic agents and strategies.
  • Apply an awareness of new data sets and the perspectives of tumor-specific clinical investigators to refine or validate current treatment algorithms.
  • Evaluate the mechanisms of action, tolerability and efficacy of promising investigational agents, and consider the implications for clinical practice.

  ACCREDITATION STATEMENT
  Research To Practice is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
  
  CREDIT DESIGNATION STATEMENT
  Video Program: Research To Practice designates this enduring material for a maximum of 15 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
  
  AMERICAN BOARD OF INTERNAL MEDICINE (ABIM) — MAINTENANCE OF CERTIFICATION (MOC)
  Successful completion of this CME activity, which includes participation in the evaluation component and a post-test, enables the participant to earn up to 15 Medical Knowledge MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for this activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
  
  Please note, these programs have been specifically designed for the following ABIM specialties: medical oncology and hematology.
  
  PRIVACY POLICY
  Personal information and data sharing: Research To Practice aggregates deidentified user data for program-use analysis, program development, activity planning and site improvement. We may provide aggregate and deidentified data to third parties, including commercial supporters. We do not share or sell personally identifiable information to any unaffiliated third parties or commercial supporters. Please see our privacy policy at ResearchToPractice.com/Privacy-Policy for more information.
  
  HOW TO USE THIS CME ACTIVITY
  Video Program: This CME activity consists of a video component. To receive credit, the participant should review the CME information, watch the video, complete the post-test with a score of 80% or better and fill out the evaluation located at ResearchToPractice.com/GMO24/Video/CME.
  
  CONTENT VALIDATION AND DISCLOSURES
  Research To Practice (RTP) is committed to providing its participants with high-quality, unbiased and state-of-the-art education and adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of an accredited continuing education activity, including faculty, planners, reviewers and others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of this activity. In addition, all activity content is reviewed by RTP scientific staff and an external, independent physician reviewer for fair balance, scientific objectivity of studies referenced and patient care recommendations.
  
  FACULTY — The following faculty reported relevant financial relationships with ineligible entities:
  
  Ghassan Abou-Alfa, MD, MBA
  Attending
  Memorial Sloan Kettering Cancer Center
  Professor
  Weill Cornell Medical College at Cornell University
  Adjunct Professor
  Trinity College Dublin (Ireland)
  New York, New York
  
  Consulting Agreements: AstraZeneca Pharmaceuticals LP, Autem Therapeutics, Berry Genomics, BioNTech SE, Boehringer Ingelheim Pharmaceuticals Inc, Bristol Myers Squibb, Eisai Inc, Exelixis Inc, Genentech, a member of the Roche Group, Incyte Corporation, Ipsen Biopharmaceuticals Inc, Merck, Merus BV, Neogene Therapeutics, Novartis, Servier Pharmaceuticals LLC, Tempus, Vector Pharma, Yiviva; Contracted Research: Agenus Inc, Arcus Biosciences, AstraZeneca Pharmaceuticals LP, BioNTech SE, Bristol Myers Squibb, Digestive Care Inc, Elicio Therapeutics, Genentech, a member of the Roche Group, Helsinn Healthcare SA, Puma Biotechnology Inc, QED Therapeutics, Yiviva; Nonrelevant Financial Relationship: Parker Institute for Cancer Immunotherapy.
  
  Emmanuel S Antonarakis, MD
  Clark Endowed Professor of Medicine
  Division of Hematology, Oncology and Transplantation
  University of Minnesota
  Minneapolis, Minnesota
  
  Advisory Committees: Aadi Bioscience, Amgen Inc, AstraZeneca Pharmaceuticals LP, Bayer HealthCare Pharmaceuticals, Blue Earth Diagnostics, Curium, Janssen Biotech Inc, Merck, Pfizer Inc, Sanofi, Tango Therapeutics, Tempus; Consulting Agreements: EcoR1 Capital LLC, HOOKIPA Pharma Inc, Lilly, Menarini Silicon Biosystems, Z-Alpha; Contracted Research: Astellas, Bayer HealthCare Pharmaceuticals, Bristol Myers Squibb, Clovis Oncology, MacroGenics Inc, Merck, Novartis, Orion Corporation, Seagen Inc; Patent Holder: QIAGEN.
  
  Natalie S Callander, MD
  Director, Myeloma Clinical Program
  University of Wisconsin Carbone Cancer Center
  Madison, Wisconsin
  
  No relevant conflicts of interest to disclose.
  
  Kristen K Ciombor, MD, MSCI
  Associate Professor of Medicine
  Division of Hematology/Oncology
  Vanderbilt-Ingram Cancer Center
  Nashville, Tennessee
  
  Advisory Committees: Bayer HealthCare Pharmaceuticals, Exelixis Inc, Incyte Corporation, Loxo Oncology Inc, a wholly owned subsidiary of Eli Lilly & Company, Merck, Personalis, Pfizer Inc, Replimune, Seagen Inc; Consulting Agreements: Merck, Pfizer Inc; Contracted Research: Array BioPharma Inc, a subsidiary of Pfizer Inc, Bristol Myers Squibb, Calithera Biosciences, Daiichi Sankyo Inc, Genentech, a member of the Roche Group, Incyte Corporation, Merck, NuCana, Pfizer Inc, Seagen Inc.
  
  Ibiayi Dagogo-Jack, MD
  Assistant Professor of Medicine
  Harvard Medical School
  Massachusetts General Hospital
  Boston, Massachusetts
  
  Consulting Agreements: AstraZeneca Pharmaceuticals LP, Bayer HealthCare Pharmaceuticals, BostonGene, Bristol Myers Squibb, Foundation Medicine, Genentech, a member of the Roche Group, Merus BV, Novocure Inc, Pfizer Inc, Roche Laboratories Inc, Sanofi, Thermo Fisher Scientific Inc; Contracted Research: Genentech, a member of the Roche Group, Novartis, Pfizer Inc; Data and Safety Monitoring Board/Committee: Vivace Therapeutics Inc.
  
  Richard S Finn, MD
  Professor, Department of Medicine, Division of Hematology/Oncology
  David Geffen School of Medicine at UCLA
  Director, Signal Transduction and Therapeutics Program
  Jonsson Comprehensive Cancer Center at UCLA
  Los Angeles, California
  
  Consulting Agreements: AstraZeneca Pharmaceuticals LP, Bayer HealthCare Pharmaceuticals, Bristol Myers Squibb, CStone Pharmaceuticals, Eisai Inc, Exelixis Inc, Genentech, a member of the Roche Group, Hengrui Therapeutics Inc, Lilly, Merck, Pfizer Inc; Contracted Research: Bristol Myers Squibb, Eisai Inc, Genentech, a member of the Roche Group, Merck, Pfizer Inc; Data and Safety Monitoring Board/Committee: AstraZeneca Pharmaceuticals LP; Speakers Bureau: Genentech, a member of the Roche Group.
  
  Matthew D Galsky, MD
  Professor of Medicine
  Icahn School of Medicine at Mount Sinai
  Co-Leader, Bladder Cancer Center of Excellence
  Associate Director, Translational Research
  The Tisch Cancer Institute
  New York, New York
  
  Consulting Agreements: AbbVie Inc, Alligator Bioscience, Analog Devices Inc, Asieris Pharmaceuticals, AstraZeneca Pharmaceuticals LP, Basilea Pharmaceutica Ltd, Bicycle Therapeutics, Bristol Myers Squibb, Curis Inc, Dragonfly Therapeutics, EMD Serono Inc, FUJIFILM Pharmaceuticals USA Inc, Genentech, a member of the Roche Group, Gilead Sciences Inc, GSK, Janssen Biotech Inc, Merck, Numab Therapeutics AG, Rappta Therapeutics, Pfizer Inc, Seagen Inc, Silverback Therapeutics, UroGen Pharma; Contracted Research: AstraZeneca Pharmaceuticals LP, Bristol Myers Squibb, Dendreon Pharmaceuticals Inc, Genentech, a member of the Roche Group, Merck, Novartis.
  
  Edward B Garon, MD, MS
  Professor
  Director, Thoracic Oncology Program
  Director, Signal Transduction and Therapeutics Research Program
  David Geffen School of Medicine at UCLA
  Jonsson Comprehensive Cancer Center
  Los Angeles, California
  
  Advisory Committees: AbbVie Inc, Arcus Biosciences, AstraZeneca Pharmaceuticals LP, Atreca, Bristol Myers Squibb, EMD Serono Inc, Gilead Sciences Inc, GSK, HOOKIPA Pharma Inc, LianBio, Lilly, Merck, Merus BV, Novartis, Personalis, QED Therapeutics, a BridgeBio company, Regeneron Pharmaceuticals Inc, Sanofi, Seagen Inc, Sensei Biotherapeutics, Sumitomo Dainippon Pharma Oncology Inc, Summit Therapeutics, Synthekine, Xilio Therapeutics, Zymeworks Inc; Contracted Research: ABL Bio, ArriVent Biopharma, AstraZeneca Pharmaceuticals LP, Bristol Myers Squibb, Daiichi Sankyo Inc, EMD Serono Inc, Genentech, a member of the Roche Group, Gilead Sciences Inc, Iovance Biotherapeutics, Lilly, Merck, Mirati Therapeutics Inc, Novartis, Prelude Therapeutics, Regeneron Pharmaceuticals Inc, Synthekine; Data and Safety Monitoring Board/Committee: Nuvalent; Sponsored Independent Medical Education: Daiichi Sankyo Inc, Ipsen Biopharmaceuticals Inc; Travel: A2 Bio, Novartis.
  
  Erika Hamilton, MD
  Director, Breast Cancer Research Program
  Sarah Cannon Research Institute
  Nashville, Tennessee
  
  Consulting Agreements — Payment Made to Institution: Accutar Biotechnology Inc, AstraZeneca Pharmaceuticals LP, Daiichi Sankyo Inc, Ellipses Pharma, Entos Pharmaceuticals, Fosun Pharma, Genentech, a member of the Roche Group, Gilead Sciences Inc, Greenwich LifeSciences Inc, Jazz Pharmaceuticals Inc, Lilly, Mersana Therapeutics Inc, MphaR, Novartis, Olema Oncology, Orum Therapeutics, Pfizer Inc, Stemline Therapeutics Inc, Theratechnologies, Tubulis, Zentalis Pharmaceuticals; Contracted Research — Payment Made to Institution: AbbVie Inc, Accutar Biotechnology Inc, Acerta Pharma — A member of the AstraZeneca Group, ADC Therapeutics, Akesobio Australia Pty Ltd, Amgen Inc, Aravive Inc, ArQule Inc, Artios, Arvinas, AstraZeneca Pharmaceuticals LP, AtlasMedx Inc, BeiGene Ltd, Black Diamond Therapeutics Inc, Bliss Biopharmaceutical, Boehringer Ingelheim Pharmaceuticals Inc, Clovis Oncology, Compugen, Context Therapeutics, Cullinan Oncology, Curis Inc, CytomX Therapeutics, Daiichi Sankyo Inc, Dantari, Deciphera Pharmaceuticals Inc, Duality Biologics, eFFECTOR Therapeutics Inc, Ellipses Pharma, Elucida Oncology Inc, EMD Serono Inc, FUJIFILM Pharmaceuticals USA Inc, G1 Therapeutics Inc, Genentech, a member of the Roche Group, Gilead Sciences Inc, H3 Biomedicine, Harpoon Therapeutics, Hutchison MediPharma, ImmunoGen Inc, Incyte Corporation, Infinity Pharmaceuticals Inc, Inspirna, InventisBio, Jacobio Pharmaceuticals Group Co Ltd, Karyopharm Therapeutics, K-Group Beta, Kind Pharmaceuticals LLC, Leap Therapeutics Inc, Lilly, Loxo Oncology Inc, a wholly owned subsidiary of Eli Lilly & Company, Lycera, MacroGenics Inc, Marker Therapeutics Inc, Mersana Therapeutics Inc, Merus, Molecular Templates, Myriad Genetic Laboratories Inc, Novartis, NuCana, Olema Oncology, OncoMed Pharmaceuticals Inc, Onconova Therapeutics Inc, Oncothyreon, ORIC Pharmaceuticals, Orinove Inc, Orum Therapeutics, Pfizer Inc, PharmaMar, Pieris Pharmaceuticals Inc, Pionyr Immunotherapeutics, Plexxikon Inc, Prelude Therapeutics, ProfoundBio, Radius Health Inc, Regeneron Pharmaceuticals Inc, Relay Therapeutics, Repertoire Immune Medicines, Seagen Inc, Sermonix Pharmaceuticals, Shattuck Labs, Stemcentrx, Sutro Biopharma, Syndax Pharmaceuticals, Syros Pharmaceuticals Inc, Taiho Oncology Inc, Takeda Pharmaceuticals USA Inc, Tesaro, A GSK Company, Tolmar, Transcenta, Treadwell Therapeutics, Verastem Inc, Zenith Epigenetics, Zymeworks Inc; Nonrelevant Financial Relationship: Verascity Science.
  
  Yelena Y Janjigian, MD
  Chief of Gastrointestinal Oncology Service
  Department of Medicine
  Memorial Sloan Kettering Cancer Center
  New York, New York
  
  Advisory Committees and Consulting Agreements: AbbVie Inc, Amerisource Bergen, Arcus Biosciences, AskGene Pharma, Astellas, AstraZeneca Pharmaceuticals LP, Basilea Pharmaceutica Ltd, Bayer HealthCare Pharmaceuticals, Bristol Myers Squibb, Daiichi Sankyo Inc, Geneos Therapeutics, GSK, Guardant Health, Imugene, Inspirna, Lilly, Lynx Health LLC, Merck, Merck Serono, Mersana Therapeutics Inc, Pfizer Inc, Seagen Inc, Silverback Therapeutics, Zymeworks Inc; Contracted Research: Arcus Biosciences, AstraZeneca Pharmaceuticals LP, Bayer HealthCare Pharmaceuticals, Bristol Myers Squibb, Genentech, a member of the Roche Group, Inspirna, Lilly, Merck, Transcenta; Data and Safety Monitoring Boards/Committees: Arcus Biosciences, Daiichi Sankyo Inc, Transcenta; Stock Options — Private Company: Inspirna; Nonrelevant Financial Relationships: Clinical Care Options, Cycle for Survival, Fred's Team, HMP Education, Imedex, MJH Life Sciences, National Cancer Institute, Paradigm Medical Communications, PeerView Institute, US Department of Defense.
  
  Eric Jonasch, MD
  Professor of Medicine
  Department of Genitourinary Medical Oncology
  The University of Texas MD Anderson Cancer Center
  Houston, Texas
  
  Consulting Agreements: Aveo Pharmaceuticals, Eisai Inc, Exelixis Inc, GSK, Ipsen Biopharmaceuticals Inc, Merck, Nikang Therapeutics Inc, Novartis, Takeda Pharmaceuticals USA Inc, Telix Pharmaceuticals Limited; Contracted Research: Arrowhead Pharmaceuticals, Aveo Pharmaceuticals, Corvus Pharmaceuticals, Merck, Nikang Therapeutics Inc, Novartis, Telix Pharmaceuticals Limited; Data and Safety Monitoring Board/Committee: Pfizer Inc.
  
  Virginia Kaklamani, MD, DSc
  Professor of Medicine
  Ruth McLean Bowman Bowers Chair in Breast Cancer Research and Treatment
  AB Alexander Distinguished Chair in Oncology
  Leader, Breast Oncology Program
  UT Health San Antonio MD Anderson Cancer Center
  San Antonio, Texas
  
  Consulting Agreements: AstraZeneca Pharmaceuticals LP, Daiichi Sankyo Inc, Gilead Sciences Inc, Lilly, Menarini Group, Puma Biotechnology Inc, TerSera Therapeutics LLC; Contracted Research: Eisai Inc; Data and Safety Monitoring Board/Committee: Sanofi; Speakers Bureaus: AstraZeneca Pharmaceuticals LP, Daiichi Sankyo Inc, Genentech, a member of the Roche Group, Gilead Sciences Inc, Novartis, Pfizer Inc, Seagen Inc.
  
  Kevin Kalinsky, MD, MS
  Professor
  Department of Hematology and Medical Oncology
  Emory University School of Medicine
  Director, Glenn Family Breast Center
  Director, Breast Medical Oncology
  Winship Cancer Institute of Emory University
  Atlanta, Georgia
  
  Advisory Committees: AstraZeneca Pharmaceuticals LP, Daiichi Sankyo Inc, Genentech, a member of the Roche Group, Gilead Sciences Inc, Menarini Silicon Biosystems, Merck, Mersana Therapeutics Inc, Myovant Sciences, Puma Biotechnology Inc, Seagen Inc, Takeda Pharmaceuticals USA Inc; Consulting Agreement: Merck; Contracted Research: Ambrx, Ascentage Pharma, AstraZeneca Pharmaceuticals LP, Gilead Sciences Inc, Novartis; Nonrelevant Financial Relationship: ADC Therapeutics (spouse).
  
  Samuel J Klempner, MD
  Associate Professor
  Massachusetts General Hospital
  Harvard Medical School
  Boston, Massachusetts
  
  Advisory Committees: Amgen Inc, AstraZeneca Pharmaceuticals LP, Bristol Myers Squibb, Coherus BioSciences, Daiichi Sankyo Inc, Merck, Mersana Therapeutics Inc, Natera Inc, Pfizer Inc, Sanofi, Servier Pharmaceuticals LLC; Consulting Agreements: Astellas, Novartis; Medical Advisory Boards (No Compensation): Debbie’s Dream Foundation, Hope for Stomach Cancer; Stock Options/Ownership — Public Companies: Nuvalent (ended 11/2022), Turning Point Therapeutics Inc (ended 6/2022); Nonrelevant Financial Relationships: American Gastroenterological Association, Degregorio Family Foundation, National Cancer Institute/National Institutes of Health, Stand Up 2 Cancer/AACR.
  
  Andrew H Ko, MD
  Professor and Associate Chief, Division of Hematology/Oncology
  University of California, San Francisco
  San Francisco, California
  
  Advisory Committees (One-Time Advisory Boards): Aadi Bioscience, Arcus Biosciences, Eisai Inc, FibroGen Inc, Genentech, a member of the Roche Group, Merus BV; Consulting Agreement: FibroGen Inc; Contracted Research (to Institution): AbGenomics, Apexigen, Astellas, Bristol Myers Squibb, Celgene Corporation, Leap Therapeutics Inc, Merck, Verastem Inc; Data and Safety Monitoring Boards/Committees: Genentech, a member of the Roche Group, Grail Inc; Nonrelevant Financial Relationships: Pancreatic Cancer Action Network, Parker Institute for Cancer Immunotherapy.
  
  Ann S LaCasce, MD, MMSc
  Director, Dana-Farber/Mass General Brigham Fellowship in Hematology/Oncology
  Associate Professor of Medicine, Harvard Medical School
  Lymphoma Program
  Dana-Farber Cancer Institute
  Boston, Massachusetts
  
  Advisory Committees: Kite, A Gilead Company, Seagen Inc; Data and Safety Monitoring Board/Committee (Does Not Take Payment): Bristol Myers Squibb.
  
  Corey J Langer, MD
  Director of Thoracic Oncology
  Abramson Cancer Center
  Professor of Medicine
  Perelman School of Medicine
  University of Pennsylvania
  Philadelphia, Pennsylvania
  
  Consulting Fees: AstraZeneca Pharmaceuticals LP, Boehringer Ingelheim Pharmaceuticals Inc, Genentech, a member of the Roche Group, Gilead Sciences Inc, GSK, Heat Biologics, Merck, Mirati Therapeutics Inc, Novocure Inc, Pfizer Inc, Regeneron Pharmaceuticals Inc, Sanofi, Takeda Pharmaceuticals USA Inc; Data Safety Monitoring Boards or Advisory Boards (Co-Chair): Amgen Inc, Oncocyte; Medical Writing: Novartis; Research Funding: AstraZeneca Pharmaceuticals LP, Boehringer Ingelheim Pharmaceuticals Inc, Inovio Pharmaceuticals Inc, Lilly, Merck, Oncocyte, Takeda Pharmaceuticals USA Inc, Trizell; Nonrelevant Financial Relationship: US Department of Veterans Affairs.
  
  Matthew Lunning, DO
  Associate Professor of Medicine
  Medical Director, Cellular Therapy
  Associate Vice Chair of Research
  Assistant Vice Chancellor for Clinical Research
  Division of Hematology/Oncology
  Department of Internal Medicine
  University of Nebraska Medical Center
  Omaha, Nebraska
  
  Consulting Agreements: AbbVie Inc, AstraZeneca Pharmaceuticals LP, Bristol Myers Squibb, Caribou Biosciences Inc, Daiichi Sankyo Inc, Fate Therapeutics, Genentech, a member of the Roche Group, Genmab US Inc, Ipsen Biopharmaceuticals Inc, Janssen Biotech Inc, Kite, A Gilead Company, Loxo Oncology Inc, a wholly owned subsidiary of Eli Lilly & Company, Nurix Therapeutics Inc, Recordati, Regeneron Pharmaceuticals Inc, Seagen Inc, Takeda Pharmaceuticals USA Inc; Research Support: Bristol Myers Squibb, Fate Therapeutics, Sana Biotechnology.
  
  Kami Maddocks, MD
  Professor — Clinical
  Director, Lymphoma Program
  Associate Division Director for Ambulatory Operations
  Division of Hematology
  Medical Director, Infusion Services
  Associate Chief Medical Officer
  Chief of Staff Elect
  The James Cancer Hospital and Solove Research Institute
  The Ohio State University Comprehensive Cancer Center
  Columbus, Ohio
  
  Consulting Agreements: AbbVie Inc, ADC Therapeutics, AstraZeneca Pharmaceuticals LP, Bristol Myers Squibb, Genentech, a member of the Roche Group, Genmab US Inc, Incyte Corporation, Janssen Biotech Inc, Kite, A Gilead Company, Lilly, MorphoSys.
  
  Rana R McKay, MD
  Associate Professor of Medicine and Urology
  Associate Director, Translational Sciences
  Interim Associate Director, Clinical Sciences
  Co-Lead, Genitourinary Oncology Program
  University of California San Diego
  Moores Cancer Center
  La Jolla, California
  
  Consulting Agreements: AstraZeneca Pharmaceuticals LP, Aveo Pharmaceuticals, Bayer HealthCare Pharmaceuticals, Blue Earth Diagnostics, Bristol Myers Squibb, Calithera Biosciences, Caris Life Sciences, Dendreon Pharmaceuticals Inc, Eisai Inc, Exelixis Inc, Johnson & Johnson Pharmaceuticals, Lilly, Merck, Myovant Sciences, Novartis, Pfizer Inc, Sanofi, Seagen Inc, Sorrento Therapeutics, Telix Pharmaceuticals Limited, Tempus; Contracted Research: AstraZeneca Pharmaceuticals LP, ArteraAI, Bayer HealthCare Pharmaceuticals, Bristol Myers Squibb, Exelixis Inc, Oncternal Therapeutics.
  
  Bradley J Monk, MD
  Medical Director, Late-Phase Research Program
  Florida Cancer Specialists & Research Institute
  Vice President and Member, Board of Directors
  GOG Foundation
  Co-Director, GOG Partners
  West Palm Beach, Florida
  
  Consulting Agreements: Acrivon Therapeutics, Adaptimmune, Agenus Inc, Akeso Biopharma Co Ltd, Amgen Inc, Aravive Inc, AstraZeneca Pharmaceuticals LP, Bayer HealthCare Pharmaceuticals, Clovis Oncology, Eisai Inc, Elevar Therapeutics, Genentech, a member of the Roche Group, Genmab US Inc, Gradalis Inc, Hengrui Therapeutics Inc, ImmunoGen Inc, Iovance Biotherapeutics, Karyopharm Therapeutics, Laekna Therapeutics, Merck, Merck KGaA, Mersana Therapeutics Inc, Myriad Genetic Laboratories Inc, Novartis, Novocure Inc, OncoC4, Panavance Therapeutics, Pfizer Inc, Pieris Pharmaceuticals Inc, Puma Biotechnology Inc, Regeneron Pharmaceuticals Inc, Seagen Inc, Sorrento Therapeutics, Tesaro, A GSK Company, VBL Therapeutics, Verastem Inc, Zentalis Pharmaceuticals; Speakers Bureaus: AstraZeneca Pharmaceuticals LP, Clovis Oncology, Eisai Inc, Genentech, a member of the Roche Group, ImmunoGen Inc, Merck, Myriad Genetic Laboratories Inc, Tesaro, A GSK Company; Nonrelevant Financial Relationship: US Oncology Research.
  
  David M O'Malley, MD
  Director and Professor
  Division of Gynecologic Oncology in Obstetrics and Gynecology
  John G Boutselis Chair in Gynecologic Oncology
  The Ohio State University and The James Comprehensive Cancer Center
  Columbus, Ohio
  
  Advisory Committees and Consulting Agreements (Personal Fees): AbbVie Inc, Adaptimmune, Agenus Inc, Arcus Biosciences, Arquer Diagnostics, AstraZeneca Pharmaceuticals LP, Atossa Therapeutics, Cardiff Oncology, Celcuity, Clovis Oncology, Corcept Therapeutics, Duality Biologics, Eisai Inc, Elevar Therapeutics, Exelixis Inc, F Hoffmann-La Roche Ltd, Genelux Corporation, Genentech, a member of the Roche Group, GSK, ImmunoGen Inc, Imvax Inc, InterVenn Biosciences, InxMed, Iovance Biotherapeutics, Janssen Biotech Inc, Jazz Pharmaceuticals Inc, Laekna Therapeutics, Leap Therapeutics Inc, Luzsana Biotechnology, Merck, Mersana Therapeutics Inc, MSD, Myriad Genetic Laboratories Inc, Novartis, Novocure Inc, OncoC4, Onconova Therapeutics Inc, Regeneron Pharmaceuticals Inc, Replimune, Roche Diagnostics, R-Pharm US, Seagen Inc, Sorrento Therapeutics, Sumitomo Dainippon Pharma Oncology Inc, Sutro Biopharma, Tarveda Therapeutics, Toray Industries Inc, Trillium Therapeutics Inc, Umoja Biopharma, VBL Therapeutics, Verastem Inc, Vincerx Pharma, Xencor, Zentalis Pharmaceuticals; Contracted Research (Institution Received Funds): AbbVie Inc, Advaxis Inc, Agenus Inc, Alkermes, Aravive Inc, Arcus Biosciences, AstraZeneca Pharmaceuticals LP, BeiGene Ltd, Bristol Myers Squibb, Clovis Oncology, Deciphera Pharmaceuticals Inc, Eisai Inc, EMD Serono Inc, Exelixis Inc, F Hoffmann-La Roche Ltd, Genentech, a member of the Roche Group, Genmab US Inc, GSK, ImmunoGen Inc, Incyte Corporation, Iovance Biotherapeutics, Karyopharm Therapeutics, Leap Therapeutics Inc, Merck, Mersana Therapeutics Inc, MSD, Novartis, Novocure Inc, OncoC4, OncoQuest Inc, Pfizer Inc, Predictive Oncology Inc, Prelude Therapeutics, Regeneron Pharmaceuticals Inc, Rubius Therapeutics, Seagen Inc, Sumitomo Dainippon Pharma Oncology Inc, Sutro Biopharma, Tesaro, A GSK Company, Verastem Inc; Nonrelevant Financial Relationships: GOG Foundation Inc, Ludwig Institute for Cancer Research Ltd, National Cancer Institute, NRG Oncology, RTOG, SWOG.
  
  Eileen M O’Reilly, MD
  Winthrop Rockefeller Endowed Chair in Medical Oncology
  Section Head, Hepatopancreaticobiliary and Neuroendocrine Cancers
  Co-Director, Medical Initiatives
  David M Rubenstein Center for Pancreatic Cancer Research
  Chair, Human Research Protection Program and IRB
  Attending Physician, Member
  Memorial Sloan Kettering Cancer Center
  Professor of Medicine, Weill Cornell Medical College
  New York, New York
  
  Consulting Agreements: AbbVie Inc, AstraZeneca Pharmaceuticals LP, Autem Therapeutics, Berry Genomics, BioNTech SE, Boehringer Ingelheim Pharmaceuticals Inc, Bristol Myers Squibb, Eisai Inc, Exelixis Inc, Genentech, a member of the Roche Group, Incyte Corporation, Ipsen Biopharmaceuticals Inc, J-Pharma Co Ltd, Merck, Merus BV, Neogene Therapeutics, Novartis, Servier Pharmaceuticals LLC, Tempus, Vector Pharma, Yiviva; Contracted Research: Agenus Inc, Arcus Biosciences, AstraZeneca Pharmaceuticals LP, BioNTech SE, Bristol Myers Squibb, Digestive Care Inc, Elicio Therapeutics, Genentech, a member of the Roche Group, Helsinn Healthcare SA, Puma Biotechnology Inc, QED Therapeutics, Yiviva; Nonrelevant Financial Relationship: Parker Institute for Cancer Immunotherapy.
  
  Joyce O’Shaughnessy, MD
  Celebrating Women Chair in Breast Cancer Research
  Baylor University Medical Center
  Chair, Breast Disease Committee
  Sarah Cannon Research Institute
  Dallas, Texas
  
  Advisory Committees and Consulting Agreements: AbbVie Inc, Agendia Inc, Aptitude Health, AstraZeneca Pharmaceuticals LP, Carrick Therapeutics, Daiichi Sankyo Inc, Eisai Inc, Fishawack Health, G1 Therapeutics Inc, Genentech, a member of the Roche Group, Gilead Sciences Inc, GSK, Lilly, Loxo Oncology Inc, a wholly owned subsidiary of Eli Lilly & Company, Merck, Novartis, Ontada, Pfizer Inc, Pierre Fabre, Puma Biotechnology Inc, Roche Laboratories Inc, Samsung Bioepis, Sanofi, Seagen Inc, Stemline Therapeutics Inc.
  
  Paul G Richardson, MD
  Clinical Program Leader and Director of Clinical Research
  Jerome Lipper Multiple Myeloma Center
  Dana-Farber Cancer Institute
  RJ Corman Professor of Medicine
  Harvard Medical School
  Boston, Massachusetts
  
  Advisory Committees: Bristol Myers Squibb, Celgene Corporation, GSK, Karyopharm Therapeutics, Oncopeptides, Sanofi; Research Grants: Bristol Myers Squibb, Celgene Corporation, Karyopharm Therapeutics, Oncopeptides, Takeda Pharmaceuticals USA Inc.
  
  Brian Rini, MD
  Professor of Medicine
  Chief of Clinical Trials
  Vanderbilt-Ingram Cancer Center
  Division of Hematology/Oncology
  Vanderbilt University Medical Center
  Nashville, Tennessee
  
  Advisory Committee: AstraZeneca Pharmaceuticals LP; Consulting Agreements: Alkermes, Aravive Inc, Arrowhead Pharmaceuticals, Athenex, Aveo Pharmaceuticals, Bristol Myers Squibb, Corvus Pharmaceuticals, Debiopharm, Eisai Inc, EUSA Pharma, Genentech, a member of the Roche Group, HiberCell, Merck, NiKang Therapeutics Inc, Pfizer Inc, Sanofi, Surface Oncology; Contracted Research: ADC Therapeutics, Adela, Arcus Biosciences, Arrowhead Pharmaceuticals, AstraZeneca Pharmaceuticals LP, Aveo Pharmaceuticals, Bristol Myers Squibb, Daiichi Sankyo Inc, Dracen Pharmaceuticals, Dragonfly Therapeutics, Exelixis Inc, Genentech, a member of the Roche Group, Gilead Sciences Inc, HiberCell, Incyte Corporation, Janssen Biotech Inc, Merck, Pfizer Inc, Pionyr Immunotherapeutics, POINT Biopharma, Strata Oncology, Surface Oncology, Tempus, VasGene Therapeutics Inc; Data and Safety Monitoring Board/Committee: AstraZeneca Pharmaceuticals LP.
  
  Jonathan E Rosenberg, MD
  Chief, Genitourinary Medical Oncology Service
  Division of Solid Tumor Oncology
  Enno W Ercklentz Chair
  Memorial Sloan Kettering Cancer Center
  New York, New York
  
  Advisory Committees: Astellas, Seagen Inc, Tyra Biosciences; Consulting Agreements: Aadi Bioscience, Alligator Bioscience, Astellas, AstraZeneca Pharmaceuticals LP, Boehringer Ingelheim Pharmaceuticals Inc, Bristol Myers Squibb, EMD Serono Inc, Emergence Therapeutics, Genentech, a member of the Roche Group, Gilead Sciences Inc, Imvax Inc, Infinity Pharmaceuticals Inc, Jiangsu Hengrui Medicine Co Ltd, Lilly, Merck, Mirati Therapeutics Inc, Pfizer Inc, QED Therapeutics, Seagen Inc, Tyra Biosciences; Contracted Research: Astellas, AstraZeneca Pharmaceuticals LP, Bayer HealthCare Pharmaceuticals, Seagen Inc; Speakers Bureaus: EMD Serono Inc, Pfizer Inc; Nonrelevant Financial Relationships: Clinical Care Options, Medscape, MJH Life Sciences.
  
  Hope S Rugo, MD
  Professor of Medicine
  Winterhof Family Professor of Breast Cancer
  Director, Breast Oncology and Clinical Trials Education
  Medical Director, Cancer Infusion Services
  University of California, San Francisco
  Helen Diller Family Comprehensive Cancer Center
  San Francisco, California
  
  Consulting Agreements: Daiichi Sankyo Inc, Eisai Inc, Napo Pharmaceuticals Inc, Viatris; Contracted Research: Ambrx, AstraZeneca Pharmaceuticals LP, Daiichi Sankyo Inc, F Hoffmann-La Roche Ltd, Genentech, a member of the Roche Group, Gilead Sciences Inc, Lilly, Merck, Novartis, OBI Pharma Inc, Pfizer Inc, Stemline Therapeutics Inc.
  
  John Strickler, MD
  Associate Professor
  Associate Director, Clinical Research – GI
  Duke University
  Durham, North Carolina
  
  Advisory Committees: AbbVie Inc, Agenus Inc, Astellas, AstraZeneca Pharmaceuticals LP, Bayer HealthCare Pharmaceuticals, BeiGene Ltd, Daiichi Sankyo Inc, Genentech, a member of the Roche Group, GSK, Jazz Pharmaceuticals Inc, Johnson & Johnson Pharmaceuticals, Lilly, Merck, Natera Inc, Pfizer Inc, Regeneron Pharmaceuticals Inc, Sanofi, Taiho Oncology Inc, Takeda Pharmaceuticals USA Inc, Xilio Therapeutics; Contracted Research: AbbVie Inc, Amgen Inc, A*STAR D3, Bayer HealthCare Pharmaceuticals, BeiGene Ltd, Curegenix, Daiichi Sankyo Inc, Erasca, Genentech, a member of the Roche Group, GSK, Leap Therapeutics Inc, Lilly, Novartis, Pfizer Inc, Revolution Medicines; Data and Safety Monitoring Boards/Committees: AbbVie Inc, BeiGene Ltd, GSK, Pfizer Inc; Stock Options — Private Company: Triumvira Immunologics.
  
  Helena Yu, MD
  Medical Oncologist
  Associate Attending
  Memorial Sloan Kettering Cancer Center
  New York, New York
  
  Consulting Agreements: AbbVie Inc, AstraZeneca Pharmaceuticals LP, Black Diamond Therapeutics Inc, Blueprint Medicines, C4 Therapeutics, Cullinan Oncology, Daiichi Sankyo Inc, Ipsen Biopharmaceuticals Inc, Janssen Biotech Inc, Taiho Oncology Inc, Takeda Pharmaceuticals USA Inc; Data and Safety Monitoring Board/Committee: Janssen Biotech Inc; Research Funding to My Institution: AstraZeneca Pharmaceuticals LP, Black Diamond Therapeutics Inc, Blueprint Medicines, Cullinan Oncology, Daiichi Sankyo Inc, Erasca, Janssen Biotech Inc, Novartis, Pfizer Inc.
  
  Andrew D Zelenetz, MD, PhD
  Medical Director, Quality Informatics
  Attending Physician
  Memorial Sloan Kettering Cancer Center
  Professor of Medicine
  Weill Cornell Medical College
  New York, New York
  
  Consulting Agreements: AbbVie Inc, Adaptive Biotechnologies Corporation, Amgen Inc, AstraZeneca Pharmaceuticals LP, Celgene Corporation, Genentech, a member of the Roche Group, Gilead Sciences Inc, Janssen Biotech Inc, MEI Pharma Inc, MorphoSys, Novartis; Contracted Research: BeiGene Ltd, Genentech, a member of the Roche Group, MEI Pharma Inc; Data and Safety Monitoring Boards/Committees: BeiGene Ltd (DMC chair), Bristol Myers Squibb, Celgene Corporation, Juno Therapeutics, a Celgene Company.
  
  MODERATOR — Dr Love is president and CEO of Research To Practice. Research To Practice receives funds in the form of educational grants to develop CME activities from the following companies: AbbVie Inc, Adaptive Biotechnologies Corporation, ADC Therapeutics, Agios Pharmaceuticals Inc, Alexion Pharmaceuticals, Amgen Inc, Array BioPharma Inc, a subsidiary of Pfizer Inc, Astellas, AstraZeneca Pharmaceuticals LP, Aveo Pharmaceuticals, Bayer HealthCare Pharmaceuticals, BeiGene Ltd, BeyondSpring Pharmaceuticals Inc, Blueprint Medicines, Boehringer Ingelheim Pharmaceuticals Inc, Bristol Myers Squibb, Celgene Corporation, Clovis Oncology, Coherus BioSciences, CTI Biopharma, a Sobi company, Daiichi Sankyo Inc, Eisai Inc, Elevation Oncology Inc, EMD Serono Inc, Epizyme Inc, Exact Sciences Corporation, Exelixis Inc, Five Prime Therapeutics Inc, Foundation Medicine, G1 Therapeutics Inc, Genentech, a member of the Roche Group, Genmab US Inc, Gilead Sciences Inc, Grail Inc, GSK, Halozyme Inc, Helsinn Healthcare SA, ImmunoGen Inc, Incyte Corporation, Ipsen Biopharmaceuticals Inc, Janssen Biotech Inc, administered by Janssen Scientific Affairs LLC, Jazz Pharmaceuticals Inc, Karyopharm Therapeutics, Kite, A Gilead Company, Kronos Bio Inc, Legend Biotech, Lilly, Loxo Oncology Inc, a wholly owned subsidiary of Eli Lilly & Company, MEI Pharma Inc, Merck, Mersana Therapeutics Inc, Mirati Therapeutics Inc, Mural Oncology Inc, Natera Inc, Novartis, Novartis Pharmaceuticals Corporation on behalf of Advanced Accelerator Applications, Novocure Inc, Oncopeptides, Pfizer Inc, Pharmacyclics LLC, an AbbVie Company, Puma Biotechnology Inc, Regeneron Pharmaceuticals Inc, R-Pharm US, Sanofi, Seagen Inc, Servier Pharmaceuticals LLC, SpringWorks Therapeutics Inc, Stemline Therapeutics Inc, Sumitomo Dainippon Pharma Oncology Inc, Syndax Pharmaceuticals, Taiho Oncology Inc, Takeda Pharmaceuticals USA Inc, TerSera Therapeutics LLC, Tesaro, A GSK Company, TG Therapeutics Inc, Turning Point Therapeutics Inc, Verastem Inc, and Zymeworks Inc.
  
  RESEARCH TO PRACTICE CME PLANNING COMMITTEE MEMBERS, STAFF AND REVIEWERS — Planners, scientific staff and independent reviewers for Research To Practice have no relevant conflicts of interest to disclose.
  
  This educational activity contains discussion of published and/or investigational uses of agents that are not indicated by the Food and Drug Administration. Research To Practice does not recommend the use of any agent outside of the labeled indications. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications and warnings. The opinions expressed are those of the presenters and are not to be construed as those of the publisher or grantors.
  
  This activity is supported by educational grants from AbbVie Inc, ADC Therapeutics, Astellas and Pfizer Inc, AstraZeneca Pharmaceuticals LP, Bayer HealthCare Pharmaceuticals, BeiGene Ltd, Bristol Myers Squibb, Daiichi Sankyo Inc, Genmab US Inc and AbbVie Inc, Janssen Biotech Inc, administered by Janssen Scientific Affairs LLC, Karyopharm Therapeutics, Legend Biotech, Lilly, Merck, Natera Inc, Novartis, Stemline Therapeutics Inc, and Taiho Oncology Inc.
  
  Release date: April 2024
  Expiration date: April 2025
  
  After completing the post-test, learners may download and review the answers here in order to identify further areas of study.