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Cancer Conference Update, Issue 1, 2013
Released May 2013

Featuring interviews with Drs Bruce D Cheson, Moshe Talpaz, Kenneth C Anderson and Brad S Kahl. (Audio Content)

CE Disclosures and Faculty Information

  • OVERVIEW OF ACTIVITY

    Hematologic oncology and related blood disorders are some of the most rapidly evolving fields in all of medicine. Results presented at major conferences from a plethora of ongoing clinical trials lead to the continual emergence of new therapeutic agents and changes in the indications for existing treatments. In order to offer optimal patient care, the practicing hematologist-oncologist must be well informed of these advances. To bridge the gap between research and patient care, this issue of Cancer Conference Update uses one-on-one discussions with Drs Cheson, Talpaz, Anderson and Kahl about the integration of key data sets presented at the 2012 American Society of Hematology Annual Meeting into the practical management of a number of hematologic cancers and related blood disorders.

    LEARNING OBJECTIVES
    • Apply emerging clinical research data to the rational selection of treatment for patients with hematologic cancers.
    • Evaluate the safety profiles and response outcomes observed in studies of next-generation proteasome inhibitors, immunomodulatory agents, histone deacetylase inhibitors, elotuzumab and other novel agents alone or in combination with approved systemic treatments for relapsed/refractory multiple myeloma.
    • Appropriately incorporate ruxolitinib into the treatment of JAK2 mutation-positive or mutation-negative myelofibrosis, with consideration of dosing based on platelet counts.
    • Integrate new therapeutic strategies into the best-practice management of Hodgkin lymphoma.
    • Recall potentially practice-changing clinical research on the care of patients with newly diagnosed, nonhigh-risk acute promyelocytic leukemia.
    • Develop an understanding of emerging efficacy and side-effect data with novel agents and combination regimens under evaluation for indolent and aggressive B-cell non-Hodgkin lymphomas.
    ACCREDITATION STATEMENT

    Research To Practice is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

    CME credit is no longer available for this issue

    CREDIT DESIGNATION STATEMENT

    CME credit is no longer available for this issue

    HOW TO USE THIS CME ACTIVITY

    This CME activity contains an audio component. The participant should listen to the audio MP3s.

    CME credit is no longer available for this issue

    CONTENT VALIDATION AND DISCLOSURES

    Research To Practice (RTP) is committed to providing its participants with high-quality, unbiased and state-of-the-art education. We assess potential conflicts of interest with faculty, planners and managers of CME activities. Real or apparent conflicts of interest are identified and resolved through a conflict of interest resolution process. In addition, all activity content is reviewed by both a member of the RTP scientific staff and an external, independent physician reviewer for fair balance, scientific objectivity of studies referenced and patient care recommendations.
     
    FACULTY — The following faculty (and their spouses/partners) reported real or apparent conflicts of interest, which have been resolved through a conflict of interest resolution process: Dr ChesonAdvisory Committee: Celgene Corporation, Cephalon Inc, Gilead Sciences Inc, Mundipharma International Limited, Onyx Pharmaceuticals Inc, Pharmacyclics Inc, Sanofi; Consulting Agreements: Celgene Corporation, Cephalon Inc, Genentech BioOncology, Mundipharma International Limited. Dr TalpazAdvisory Committee: Bristol-Myers Squibb Company, Novartis Pharmaceuticals Corporation, Pfizer Inc, Sanofi; Contracted Research: Abbott Laboratories, Bristol-Myers Squibb Company, Celgene Corporation, Incyte Corporation, Millennium: The Takeda Oncology Company, Novartis Pharmaceuticals Corporation, Sanofi; Speakers Bureau: Novartis Pharmaceuticals Corporation. Dr AndersonAdvisory Committee: Bristol-Myers Squibb Company, Celgene Corporation, Gilead Sciences Inc, Onyx Pharmaceuticals Inc, Sanofi; Other Remunerated Activities: Acetylon Pharmaceuticals Inc. Dr KahlAdvisory Committee: Celgene Corporation, Cephalon Inc, Genentech BioOncology, Millennium: The Takeda Oncology Company, Roche Laboratories Inc; Contracted Research: Abbott Laboratories, Cephalon Inc, Genentech BioOncology.

    EDITORDr Love is president and CEO of Research To Practice, which receives funds in the form of educational grants to develop CME activities from the following commercial interests: AbbVie Inc, Algeta US, Allos Therapeutics, Amgen Inc, ArQule Inc, Astellas, Aveo Pharmaceuticals, Bayer HealthCare Pharmaceuticals, Biodesix Inc, Biogen Idec, Boehringer Ingelheim Pharmaceuticals Inc, Bristol-Myers Squibb Company, Celgene Corporation, Daiichi Sankyo Inc, Dendreon Corporation, Eisai Inc, EMD Serono Inc, Foundation Medicine Inc, Genentech BioOncology, Genomic Health Inc, Gilead Sciences Inc, Incyte Corporation, Lilly USA LLC, Medivation Inc, Merck, Millennium: The Takeda Oncology Company, Mundipharma International Limited, Novartis Pharmaceuticals Corporation, Onyx Pharmaceuticals Inc, Prometheus Laboratories Inc, Regeneron Pharmaceuticals, Sanofi, Seattle Genetics, Spectrum Pharmaceuticals Inc and Teva Oncology.

    RESEARCH TO PRACTICE STAFF AND EXTERNAL REVIEWERS — The scientific staff and reviewers for Research To Practice have no real or apparent conflicts of interest to disclose.

    This educational activity contains discussion of published and/or investigational uses of agents that are not indicated by the Food and Drug Administration. Research To Practice does not recommend the use of any agent outside of the labeled indications. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications and warnings. The opinions expressed are those of the presenters and are not to be construed as those of the publisher or grantors.

    This activity is supported by educational grants from Genentech BioOncology/Biogen Idec, Incyte Corporation, Onyx Pharmaceuticals Inc and Seattle Genetics.

    Hardware/Software Requirements:
    A high-speed Internet connection  
    A monitor set to 1280 x 1024 pixels or more
    Internet Explorer 7 or later, Firefox 3.0 or later, Chrome, Safari 3.0 or later
    Adobe Flash Player 10.2 plug-in or later
    Adobe Acrobat Reader
    (Optional) Sound card and speakers for audio

    Last review date: May 2013
    Expiration date: May 2014

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Cancer Conference Update, Issue 1, 2013
Released May 2013

Featuring interviews with Drs Bruce D Cheson, Moshe Talpaz, Kenneth C Anderson and Brad S Kahl. (Audio Content)

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